Lesión cerrada de órgano sólido y tromboprofilaxis farmacológica temprana: revisión sistemática
DOI:
https://doi.org/10.35381/s.v.v10i2.5084Palabras clave:
tromboembolismo venoso, traumatismos abdominales, anticoagulantes, (Fuente: DeCS).Resumen
La lesión cerrada abdominal de órgano sólido manejada de forma no operatoria exige equilibrar el riesgo hemorrágico inicial con la prevención del tromboembolismo venoso. Objetivos: Sintetizar la evidencia sobre efectividad y seguridad de la tromboprofilaxis farmacológica temprana frente al inicio tardío en lesiones hepáticas, esplénicas o renales por trauma cerrado. Métodos: Se realizó una revisión sistemática sin metaanálisis, siguiendo PRISMA 2020. La búsqueda se efectuó en PubMed/MEDLINE, Embase, Scopus, Web of Science, Cochrane Library y LILACS. Resultados: La tromboprofilaxis temprana, en particular durante las primeras 24–48 horas, se asoció con menor frecuencia de eventos tromboembólicos en pacientes seleccionados. Conclusiones: La evidencia sugiere beneficio del inicio temprano en pacientes estables y sin sangrado activo, aunque no debe generalizarse a lesiones de alto riesgo.
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Derechos de autor 2026 Steven Josue Alcivar-Zambrano, Valeria Zila Oñate-Chang, Rogelio Andrés Leyton-Acuña, Felix Jossue Solano-Honores
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